Objective: To evaluate the value of dynamic contrast enhanced MR imaging in prediction of preoperative histological subtypes of renal cell carcinoma.
Methods: Twenty patients with renal masses diagnosed on ultrasound or CT were included. All patients subjected to DCE MRI perfusion study after taking informed consent. Patient with low GFR and history of contrast allergy were excluded. The time signal intensity curve (TIC) of the lesion was created with calculation of enhancement ratio (ER), and washout ratio (WR).
Results: The subtypes of RCC were as follows: clear cell carcinomas (n=10), papillary carcinomas (n=6) and chromophobe carcinomas (n=4). The mean ER of clear cell, papillary and chromophobe RCC were 177±18.6, 44±5.05 and 119±7.14 respectively. The mean WR of clear cell, papillary and chromophobe RCCs were 30±3.4, 47±8.9 and 43±2.3, respectively. There was a significant difference in ER (P=0.001) and WR (P=0.001) between clear cell RCC and other subtypes of RCC.
Conclusion: Dynamic contrast enhancement MR Imaging analysis is feasible and can potentially be used to differentiate ccRCC from pRCC with high accuracy.
Impact Factor
2022: 6.012
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