Aim: To evaluate the efficacy of two antifungal agents incorporated into denture adhesive against candidainfection.
Material and Methods: Forty five acrylic disks were fabricated simulating the denture. They were divided into three groups of 15 each. Group 1 Nystatin mixed with denture adhesive powder, Group 2 Grape seed extract with denture adhesive powder and an untreated group. These were kept overnight. Inoculation of candida albicans done and further plating of specimens done (on sabouraud’s dextrose agar) to check for candidal growth.
Result: Nystatin showed very high anti candidal activity and grapeseed extract showed no anti candidal activity
Conclusion: Inclusion of Nystatin into denture adhesive powder will help prevent candidal infection in denture wearers
Impact Factor
2022: 6.012
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