Efficacy of povidone iodine vs hydrogen peroxide as denture disinfectants- in vitro study

Hydrogen peroxide is a widely used antimicrobial agent. It is used in both liquid and gas form for preservative, disinfection and sterilization applications. Its advantages include its potent and broad spectrum antimicrobial activity, flexibility in use, and safety profile in comparison to other microbiocides. Hydrogen peroxide has been shown to be effective against all forms of microorganisms, including dormant forms of known high resistance such as bacterial spores and protozoal cysts, and also infectious proteins such as prions depending on the specific use of the chemical. Povidone iodine is recognized as an effective broad spectrum biocidal agent, whose in vitro biocidal activity has been studied for years against bacteria, yeast, mould viruses, fungi, protozoa, actinomycetes and rickettsia. Typical iodine solutions present significant oral toxicity, but this complex exhibits markedly lower toxicity, being less hazardous in case of accidental ingestion. The results obtained from both methods were consistent with each other.When tested against the two controls, it was found that both disinfectants had similar disinfecting properties.