Background: Uterine myomas/leiomyomas are very common in women of childbearing age. Intramural myomas are the most frequent (58 -79%) amongst all observable uterine myomas Several studies have established the advantages of Lap. Myomectomy. But controversies exist when it comes to operate multiple myomas laparoscopically concerning excessive blood loss, prolonged operation time & hospital stay, postoperative complications. Many new methods have already come up to prevent intraoperative blood loss in Lap. Myomectomy like Uterine artery ligation, usage of oxytocin, vasopressin etc. Objectives: To compare Bidirectional Barbed sutures with Conventional sutures in Lap. Myomectomy with respect to surgical outcomes in patients. Study design: Sixty Eight patients with one to three symptomatic myomas were divided into two groups. Myoma bed was sutured either with bidirectional barbed sutures or continuous conventional sutures (Vicryl). The surgeon assessed the degree of suturing difficulty using a visual analog scale ranging from 1 (least difficult suturing) to 10 (most difficult suturing). Results: Suturing with barbed suture was easier than suturing with conventional suture. Suturing time of the myoma bed was significantly shorter in the barbed suture group (15.09+/- 4.8 VS 28.07+/- 6.02; P Value 0.038). Operative time was comparable between both groups (69.15+/-12.78 VS 80.21+/-15.68; P Value 0.021).The mean intraoperative blood loss was significantly higher in conventional suture group (100.09 +/- 200+/- 90.56 P Value 0.011) Conclusion: The bidirectional barbed suture facilitates suturing of the myoma bed during laparoscopic myomectomy. Compared with conventional suture, bidirectional barbed suture reduces the operation time, suturing the myoma bed time and the intraoperative blood loss.