Oxidative stress is a physiological process in the human system, which is necessary for the sustainability and viability of the organism, however when this normal process is altered by any diseases process or imbalance in curbing the free radicles causes the system to react more vulnerably. This imbalance or antioxidant defect mechanism in the body due to any Aetiology factore, paves the way for more damages to the system, which finally results in a disease state, showing various clinical features .Various pathologies are directly or indirectly linked to this process. A deeper understanding is necessary to prevent such imbalance, which culminates in various systemic conditions.