Vanga (Shukra Loha) is a unique metal mentioned in Ayurvedic lexicon with indication in Mutrakriccha after converting it to Vanga Bhasma. Mutrakriccha is a condition of urogenital system with dysuria as a prime symptom which includes urinary tract infection. As manifestation of Mutrakriccha and lower urinary tract infection are similar, an attempt has been made in the present study to evaluate the anti-microbial efficacy of vanga bhasma on three pathogens viz. Streptococcus aureus, Candida albicans and E.coli. by in vitro method. Two samples of Vanga Bhasma have been prepared as per the reference of Rasa Tarangini for the present study. Disc diffusion method was adopted for the present study and three readings were noted at 24hrs, 48hrs and 72 hrs after initial inoculation as well as secondary inoculation. Results indicated that both the samples have shown anti-microbial activity against E.coli with inoculums of 1.4 x 10^2 cells/ml but no anti-microbial activity was shown against the other two pathogens viz. Streptococcus aureus and Candida albicans. So, it can be concluded that both the samples of Vanga Bhasma Sample 1 and Sample 2 are having antibacterial activity against Esherichia coli. as no growth was found in all the cultures after 60 hours of inoculation and Vanga Bhasma can be successfully used to treat urinary tract infection caused due to E.coli. infection.
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