Human cysticercosis is caused by Cysticercus cellulosae, larvae of a tapeworm, Taenia solium. Cysticercosis can involve any tissue in the body; the most common affected sites are central nervous system, subcutaneous tissue, eyes, and muscles. Symptomatic involvem ent of isolated skeletal muscle by solitary cysticercosis cyst is extremely rare. We present a case report of isolated involvement of calf muscles with cysticercosis presenting as acute calf pain and the management that follows.