Objective: This study aimed to evaluate the clinical spectrum of neurologic complications and their outcome in patients of dengue virus infection (DENV).
Introduction: Dengue, an acute viral disease transmitted by Aedes mosquito’s .It is highly endemic in many tropical and subtropical areas of the world. Neurological complications of dengue infection have been observed more frequently in the recent past and some studies highlighted varied neurological complications arising in the due course of dengue illness. In this retrospective study, we report various neurological complications observed in patients of dengue fever. Materials and Methods: The patients presenting with neurological complications with positive serology (IgM antibody) for dengue infection were consecutively recruited from the Department of Medicine. These patients were subjected to a detailed clinical evaluation, laboratory assessment including blood count, hematocrit, coagulation parameters, biochemical assays, serology for dengue fever, enzyme-linked immunosorbent assay for human immunodeficiency virus and other relevant investigations.
Results: 22 patients with neurological complications associated with confirmed dengue infection were observed during the study period. Of the 22 patients, eleven patients had encephalopathy, four had encephalitis, three patients were consistent with the diagnosis of intra cranial hemorrhage, one had hypokalemic paralysis associated with dengue fever, one had ischemic stroke, 1 had G.B.S. and one had optic neuritis.
Conclusion: Dengue fever was associated with widespread neurological complications.
Impact Factor
2022: 6.012
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