The earth is brimming with viruses. Co-infection with respiratory viruses and SARS-CoV-2 raising danger bells around the world. The world is living on the brink.COVID-19, an exciting outstanding pandemic co-infected with respiratory viruses, which demands crucial public health Intervention. The extent of co-infections of SARS-CoV-2 with other respiratory viruses remains unknown. Data on the prevalence and outcomes of co-infection and super infection are limited. The most significant challenge raised by co infection is perhaps the unsuitable propagation of recombination viruses through the interchange of genetic material amidst different strains. Influenza virus is a habitual pathogen that causes pneumonia in winter. It was found clinically that very few patients were diagnosed with both COVID-19 and influenza virus Rhinoviruses and coronaviruses are perceived as the significant source of the common cold syndrome.