Low back pain affects people of all ages and is a major contributor to the global disease burden. Despite advances in assessment and treatment methods, researchers and clinicians alike continue to face difficulties in managing low back pain. The large variation in manifestations, possible causes, precipitating and maintaining factors, course, prognosis, and consequences in terms of activity interference and quality of life is one reason for the limited success in identifying effective treatments. Increasing evidence suggests that central pain-modulating mechanisms and pain cognitions play important roles in the development of chronic, disabling low back pain. Cost, health-care use, and disability from low back pain vary significantly across countries and are influenced by local culture and social systems, as well as beliefs about cause and effect.
Impact Factor
2022: 6.012
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