Stafne bone cavity is a rare mandibular defect with unknown etiology, often defined as static lesions located in the angle of the mandible. It is characterized by a round or ovoid, well-defined border, unilocular radiolucency. Controversy always remained amongst the
maxillofacial surgerons whther to go for surgical intervention or not. This article describes the case of a 37-year-old patient, in whom a Stafne cyst showed a significant enlargement, reaching a size that necessitated surgical intervention because of the risk of pathological fracture. A literature search showed similar cases, where progression in the size of a stafne cyst could be radiographically documented. Consequently, the recommended management of these pseudocysts should be reconsidered.