To formulate a curriculum system for applied undergraduate clinical medicine in China, Chinese applied medical school should adhere to the principles of science, rationality and practicality, guided by the Outline of the National Entrance Examination of Comprehensive Western Medicine for Master of Clinical Medicine and two outlines, to formulate a curriculum system. The system includes basic medicine, clinical medicine, preventive medicine and humanistic medicine, including 29 compulsory courses with more credits, harder and stricter examinations (including 7 core compulsory courses), 10 elective courses with less credits, simple and easy examinations. If the undergraduate students of applied clinical medicine can study seriously and efficiently, and fully meet the requirements of this curriculum system, these students can easily pass the entrance examination for master of clinical medicine and the medical licensing examination, and even those who do not learn well can easily pass the recruitment examination of class Ⅱ grade B hospital in China and the medical licensing examination. If this can be done, the applied medical schools can successfully cultivate applied clinical medicine undergraduate talents who can meet the needs of hospitals and are easy to obtain employment, or provide clinical medicine graduate students for higher medical schools.