Lead is one of the ubiquitous and versatile metallic elements which humans are exposed inevitably. We are presenting a male patient of occupationally acquired lead exposure causing him to have severe anaemia and status epilepticus due to severe calcification of cortical gyri and subcortical regions as evidenced through higher levels of serum lead levels. Imaging of the brain has highlighted the importance of screening of the people for lead in the peripheral blood with classical radiological manifestations.