Periodontal regeneration is defined as the reproduction or reconstitution of a lost or injured part to restore the architecture and function of the periodontium. The ultimate goal of periodontal therapy is to regenerate the lost periodontal tissues caused by periodontitis. For complete regeneration, delivery of growth factors in a local environment plays an important role as an adjunct to bonegrafts50.Injectable Platelet rich fibrin (I-PRF) is considered as third-generation platelet concentrate, consisting of liquid concentrate of platelets, centrifuged at the lower centrifugation speed for lesser time with higher long-term releasing rate of various growth factors, easier manipulation with excellent healing properties. Hence, the aim of the present study is to investigate the clinical and radiological (bone fill) effectiveness of autologous I-PRF in combination DFDBA bone graft material and the DFDBA material alone in the treatment of intra bony defects.
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2022: 6.012
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