An approach for Poly Herbal Formulations (PHS) in managing Diabetes mellitus (DM) has drawn attention among numerous scientists all over the world. In spite of remarkable advancement in conventional medicine, DM relentlessly affects mankind and considered to be one of the major causes leading to morbidity and mortality all over the world. While on the other hand, PHF are attained popularity, particularly in the management of DM considering to its fewer side effects and inexpensiveness. The Indian Traditional System of Medicine (ISM) offers a diverse PHF in the treatment of this crippling disease. In this review, the authors have focused on research studies carried on PHF used for ant diabetes along with selection of plants, concept, merits and limitations of PHF.