Background: Timely prevention is need of the hour in patients with STEMI. The CHADS2 and CHA2DS2-VASc are clinical scores used to guide antithrombotic therapy in patients with non-valvular AF and include similar risk factors for the development of coronary artery disease (CAD) as well. Factors comprising CHA2DS2-VASc-HSF score can predict severity of CAD in patients with STEMI.
Aim: To investigate the association of higher CHA2DS2-VASc and CHA2DS2-VASc-HSF scores with CAD severity on angiography as assessed by SYNTAX score in patients with STEMI.
Material and Methods: Total of 462 patients of STEMI were included in the study meeting inclusion criteria. Study population included of 240 males and 222 females. All the study patients were divided into three SxS tertiles.
Results: Mean CHA2DS2-VASc and CHA2DS2-VASc-HSF scores according to Syntax score tertiles and number of vessels involved and correlation were evaluated. Both CHA2DS2-VASc and CHA2DS2-VASc-HSF scores were positively correlated with SYNTAX score and number of diseased vessels; but CHA2DS2-VASc-HSF score had a stronger correlation out of two scores.
Conclusion: CHA2DS2-VASc and CHA2DS2-VASc-HSF scores are positively correlated with anatomic severity of CAD.