Context: Diabetes mellitus increases susceptibility to candidiasis for which chlorhexidine has proven to be effective but has side effects like staining, dysgeusia. So, citrus aurantium (bitter orange) a natural product with no known side effects can be used to prevent candidiasis in diabetes patients as it is proven to be effective in various oral diseases.
Aims: To evaluate the efficacy of orange peel extract mouthwash when compared with 0.2% Chlorhexidine mouthwash and distilled water on oral candida albicans (CA) in type II diabetic patients.
Methods and Material: 15 type-II diabetic patients were randomly divided into 3 groups of 5 each. Group 1-Distilled water, Group 2-0.2% chlorhexidine mouthwash and Group 3- Orange peel extract mouthwash. Swab test was done before and after the use of distilled water and mouthwashes.
Statistical analysis used: Kruskal Wallis ANOVA and Spss version 22.0
Results: Respective mouthwashes when compared with distilled water (placebo) showed statistically significant decreased candidal count when compared to placebo. Both the mouth washes were effective in decreasing the CA count, which was statistically significant (p > 0.05).when mouthwashes were compared results stated that they were equally potent and no statistical significance was noted.
Conclusions: Orange peel extract mouthwash was found to be as effective as chlorhexidine mouthwash in reduction of CA whereas placebo showed no decrease in CA count.
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2022: 6.012
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