This paper discusses preliminary review on the medicinal plants and traditionaluse of it by the Yemeni people in order to provide a comprehensive documentation for future investigations and suggest perspectives for conservation and management of medicinal plants of Yemen,due to over-exploitation of medicinal plants at an alarming rate. The survey of literature showed that a total of 51 species belong to 24 families and 42 genera, the most important families are Fabaceae (10 species, 7 genera), Solanaceae (7 species, 7 genera)and Euphorbiaceous (4 species, 3 genera). The investigation for medicinal plant diversity within these families revealed that many of these species are used by local and several tribal people including medicinal healers for curing more than 120 ailments. Each species hasa scientific name, local name, family, ailments to be treated and the used part.