Evaluation of the efficacy of autogenous bone graft and platelet- rich fibrin in the treatment of periodontal intrabony defects

Aim: To evaluate the efficacy of autogenous bone graft and autologous Platelet- Rich Fibrin (PRF) in the management of periodontal intrabony defects.
Materials & Method: A total of 24 intraoral sites from the patients suffering from moderate to severe periodontitis with clinical and radiographic evidence of angular defects were selected. 12 defects were treated with autogenous bone graft (Group I) and 12 with autologous platelet rich fibrin (PRF) (Group II). Clinical parameters (i.e. probing pocket depth (PPD) and relative attachment level (RAL)) and radiological parameters (i.e. distance from CEJ to base of defect, CEJ to alveolar crest and crest to base of defect) were recorded at baseline, 3 months, 6 months and 9 months post operatively.
Results: A statistically significant PPD reduction and gain in RAL was recorded in both groups from baseline to 3 months, 6 months and 9 months. Defect fill was statistically significant from baseline to 6 months and 9 months in both the groups. However, defect fill was statistically significant from baseline to 3 months in group II only.
Conclusion: The autologous Platelet-Rich Fibrin (PRF) can be used effectively in the treatment of periodontal intrabony defects.