The mosquitocidal activity of Ageratina adenophora fractions was controlled on malarial vector, Anopheles stephensi. In the ovicidal experiment, 100% mortality was exerted by important fraction 6, 5 and 4 tested at 40, 50 and 60 ppm. Among this fraction 6 was found to be most effective for pupicidal activity provided 23.73, 27.92 and 30.00 at 25, 50 and 75 ppm. Furthermore, maximum repellency of fraction 6 and 5 tested were 0.25, 0.50 and 0.75 mg/cm2 at 40, 80, 120, 160, 200 and 240 minutes. We hypothesized that fraction 6 was provides malarial control for the mosquitocidal activity of A. adenophora compounds against An. stephensi.