Background: HIV/AIDS remains one of the world's most significant public health challenges. The goal of ART is to achieve maximal and durable suppression of virus replication. Adherence plays a very important role in success of antiretroviral therapy.Objective: to systematically assess the data of adherence and its influencing factors to antiretroviral therapy (if any) in HIV/AIDS patients. Design: systematic review and meta-analysis. Material and methods: PubMed/Medline and global health library database were used to search the literature. The major study characteristics were extracted i.e. study design, sample size, location and setting, adherence rate, etc. Results: There were ten cross-sectional studies enrolling 3657 participants. Treatment adherence found equal {OR:1.04(95% CI[0.875-1.246])} in both male and female and 0.6 times more {OR:0.67[95% CI(0.558-0.806)]} in age group less than 40 years as compare to age group more than 40 years. 54% {OR:0.56(95%CI[0.494-0.634])} of treatment adherence was found in the absence of most prevalent factors. Discussion: This systematic review and meta-analysis to summarize the data of ART adherence and factors influencing treatment adherence. Conclusion: Patients on ART face multiple barriers to adherence.Range of reasons for nonadherence to ART, including alcoholism, drug side-effects, long distance to travel to hospital, forgetfulness, etc.
Impact Factor
2022: 6.012
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