In middle ear surgery under Local anesthesia with monitored Anesthesia Care, Dexmedetomidine, a newer drug seems to be a better choice than the age old traditional regime. Local anaesthesia with sedation is a well established approach used for Tympanoplasty1. The comfort of patient as well as surgeon play important role throughout the surgery which aids to Anaesthesiologists’ satisfaction 2. In this study, satisfaction score and effectiveness of sedation with Dexmedetomidine were compared with a combination of Intra venous (IV) Fortwin- Phenargan.