Hibiscus plantifolius is a shrub with various medicianl uses and belongs to the Malvaceae family. Objective of the present work was to evaluate Methanol extract of Hibiscus plantifolius (MEHP) stems for possible in-vitro antioxidant activities. Antioxidant activity of the extract was evaluated by using Diphenyl picryl hydrazyl (DPPH) radical scavenging, Nitric oxide (NO) radical scavenging, super oxide free radical scavenging & Hydroxide free radical scavenging. Current investigation was reported that selected plants extracts such as methanolic extract of Hibiscus plantifolius was exhibited greater neutralization of DPPH*, NO*, SO* and OH* free radicals and also activity compared with standard curcumin. The antioxidant activity was exhibited due to presence of flavonoids and tannins, phenolic compounds which was present methanolic extract of Hibiscus plantifolius.