Purpose of the Study: First aid is the initial care provided for an acute illness or injury. It is usually provided by a bystander who remains in close proximity to the victim. The main objective of the study is to evaluate the effectiveness of educational intervention on the first aid among high school students in rural Guntur.Materials and Methods: A total of 419, 7th, 8th and 9th standard students were given self-administered questionnaire for assessingtheir baseline knowledge about management of common injuries followed by educational intervention with a self-constructed teaching module. Post intervention evaluation of their knowledge acquisition was done after 15 days with same questionnaire. Results: The baseline knowledge on the management of common injuries was found to be insufficient among the school students. Less than half the students knew the management of common injuries like insect bite (22.6% in government school and 29% in private school), snake bite (39.1% in government school and 22.6%) in private school) where the scores appreciably improved during post intervention.Chi square test and McNemars test was done to compare the pre and posttest scores regarding knowledge and attitude of thestudents about first aid, and there was a significant change in knowledge in post-test score compared to pre-test score. There is high effective impact on training program.Conclusion: Inculcating first-aidtraining in the school curriculum can be a good investment in ensuring proper and timely management of common injuries for both the school children as well as the community at large.