Experiments were conducted for micropropagation of endangered medicinal plant Leptadaenia reticulata (Retz.) Wight &Arn using Nodal explants by modified MS medium. The explants of Leptadaenia reticulata (Retz.)Wight.&Arn started growing in MS medium supplemented with NAA in combination with BAP within three weeks. The highest percentage and maximum number of shoot induction i.e6 shoots per explantfrom nodal segment was observed on MS medium supplemented with NAA (2.00mg/l) with BAP (4.0mg/). The pre3sent investigation can be very useful for conservation of this endangered medicinal plant.