Rojamoggu Lehyam (RML) is a polyherbal siddha medicine. RML is used in treating gastritis and peptic ulcer for more than 3 decades.The present study is made to investigate the phytochemical bio active components present in the aqueous extract. The extract is prepared by the standard procedure. This study is the initial level of understanding the types of bio active compounds present in RML and further work is to be carried out to find
out the more medicinal efficacy by other standard methods. The results of this study shows that the carbohydrates, cardiac glycosides, saponins, phenols, tannins, flavonoids, diterpenes, gum mucilage, fixed oils & fats were present and absence of alkaloids, phytosterols, proteins & amino acids and quinines in the RML aqueous extract.