The present study was planned to assess the in vitro antihelmintic properties of Desmodium scorpiurus leaf extracts in comparision with antihelmintic drug Piperazine citrate. The study on in vitro anthelmintic properties of different solvent extracts viz. hexane, chloroform, ethyl acetate and methanol were carried out against mature Pheretima posthuma. Anthelmintic activity of the plant extract revealed that all the solvent extracts offered a significant anthelmintic activity except hexane extract in a dose dependent manner. The methanol extract of the plant had a maximum effect on P. posthuma as it required 24.33 min to paralyse and 30.66 min to cause death at 10 mg mL-1 concentration. The negative control DMF was ineffectual to P. posthuma, while piperazine citrate standard caused parlalysis at 11.33 min and death at 13.33 min. Further, studies on D. scorpiurus are required to identify the active principle responsible for the anthelmintic property of the plant.
Impact Factor
2022: 6.012
This work is licensed under a