Unusual variant of calcifying cystic odontogenic tumors – report of 3 cases and review of diagnostic and therapeutic approach

Calcifying cystic odontogenic tumor (CCOT) is defined as a benign cystic neoplasm of odontogenic origin, characterized by ameloblastoma-like epithelium, with ghost cells within the epithelial lining or fibrous capsule that may undergo calcification. The calcifying odontogenic cyst (COC) account nfor only 1%-2% of all odontogenic tumors, and only 2%-14% of all COCs are solid tumors. Dentogenic ghost cell tumor is a solid neoplastic clinicopathological variant of COC and a rare odontogenic tumor. Owing to its rarity, there are few clinical series evaluating the biological behavior of COC and its variant. The aim of this case series is to present the surgical management of calcifying cystic odontogenic tumors and find out whether conservative approach (Enucleation with peripheral osteotomy followed by chemical cauterization) is sufficient for the management of CCOT instead of surgical resection of tumor. In parallel, clinical and radiographic findings as well as histological features are outlined and discussed along with review of the existing literature.