Purpose: This study was undertaken to compare three modalities of radiotherapy in pituitary tumours in terms of temporal lobe sparing and target volume coverage so as to choose the best modality for the treatment.
Methods and Materials: A total number of 22 patients were included in the study and after CT simulation, all three treatment plans were generated for all the patients. Plans were compared based on DVH characteristics and PTV coverage and OAR sparing were compared among various other parameters. The plan best optimized was chosen for treatment delivery.
Results: 3DCRT, IMRT and VMAT resulted in equally optimal PTV coverage but the VMAT plans were the best in sparing temporal lobes and other OARs. The temporal lobe sparing was trending towards significance though it could not attain statistical significance. This was attributed to difference in plan optimization methods when comparing with other studies.
Conclusion: In our study VMAT showed better sparing of temporal lobes and other OARs while offering equivalent PTV coverage in comparison to IMRT and 3DCRT.
Impact Factor
2022: 6.012
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