Synthesis of silver nanoparticles from phytoextracts and testing their potential anticancer activity

Nanoparticles has gained importance in Nanotechnology for its unique properties and exhibiting medicinal activities. Size of these nanoparticles is one of the major factor for its applications in various fields. Synthesis of nanoparticles by chemical method becomes accountable for toxicity and hence Green synthesis is eco-friendly. In this study, Silver nanoparticles are synthesized from Myristica malabarica, Vernonia amygdalina and Zanthoxylum ovalifolium, an Indian flora found in Western Ghats ecosystem rich in secondary metabolites. The extracts of these medicinal rich plants when added to different concentration of silver nitrate yields Silver nanoparticles which upon visualization by UV-Visible Spectrophotometer had a characteristic peak between 410-440nm, the ideal wavelength range for Silver nanoparticles to exhibit maximum absorbance due to its Plasmon resonance frequency phenomenon. The characterization using Dynamic Light scattering, Fourier Transform Infrared Spectroscopy and Scanning Electron Microscope techniques allowed its study against breast cancer cell lines to test their anticancer ability. This present study of Green synthesis aimed at less toxicity and eco-friendly environment.