Synthesis, characterization and biological evaluation of some schiff bases from 2-amino thiazole with heterocyclic carbaldehyde by brownstd acid as catalyst

A novel derivatives of schiff bases were synthesized from some heterocyclic aromatic aldehydes with 2-Amino Thaizole in presence of methane sulfonic acid Which was synthesized from substituted phenacylbromides with thiourea in acid medium . All the newly synthesized compounds were evaluated by advanced spectroscopic data (1H NMR, 13C NMR &LC-MS) and the structural determination can be estimated by elemental analysis. Besides all the newly synthesized compounds were examined by their biological activity.