Introduction: Vitamin B12 plays a significant role in maturation of Red Blood Cells as well as nerve functions. Its diagnostic role in psychiatric patients of depression and schizophrenia has not been explored much.
Aims & Objectives: The present study was planned to explore the significance of serum vitamin B12 & iron indices in patient of depression & schizophrenia.
Material & Method: 50 psychiatric patients diagnosed for depression and schizophrenia visiting the Out-Patient department of Psychiatry were enrolled for the study. 50 age and sex matched healthy individuals contributed the control group. Serum levels of Vitamin B12, Hemoglobin, iron and Total Iron Binding capacity (TIBC) were estimated and compared with those of healthy control group.
Result: The present study reported significantly low levels of Serum vitamin B12, hemoglobin and iron levels in both depression and schizophrenia patients as compared to healthy control group. However, serum TIBC levels exhibited no significant difference. Conclusion: The study suggests that vitamin B12 deficiency and anemia can both be a causative factor for development of depression or schizophrenia. Evaluation of these parameters in depression and schizophrenia patients is therefore, recommended.
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2022: 6.012
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