A study of sequential organ failure assessment score as a prognostic marker in patients with sepsis in intensive care unit

Objective:
• To study the demographic profile of patients with sepsis and multiple organ dysfunction syndrome in patients with intensive care units.
• To evaluate the use of SOFA Score for predicting the mortality in patients with severe sepsis.
• To evaluate the use of MAX SOFA and DELTA SOFA for assessing the outcome of patients with severe sepsis.
Materials and Methods: A sample of 100 patients who were admitted to intensive care units and fulfilling the inclusion criteria were selected for this study from the tertiary care hospital, Ahmedabad, between September 2020 - September 2021 with suspected/confirmed sepsis. It was a prospective observational study.
Results: SOFA Score at 48 hours, 96 hours, max SOFA, Δ SOFA showed mortality with a P-value <0.001 which is statistically significant. Hence use of SOFA score, Δ SOFA score, and MAX SOFA score are good predictors of outcome in patients of sepsis.
Conclusion: Sequential assessment of organ dysfunction during the first few days of ICU admission is a good indicator of prognosis. SOFA score at 48 hours and MAX SOFA score, as well as Δ SOFA score, are useful predictors of the outcome as compared to SOFA score at admission.