Study of liver function tests in hyperthyroid patients

Aim: To study liver function tests in hyperthyroidism
Materials and Methods: 80subjects in the age group of 20-65 years were taken from the outpatient department of Government Medical College, Jammu and liver function tests including serum alanine aminotransferase, serum aspartate aminotransferase, serum bilirubin and serum albumin were evaluated in these subjects.Thyroid function tests were also determined.
Results: There is significant difference in mean AST (aspartate aminotransferase) and mean ALT (alanine aminotransferase) between euthyroid and hyperthyroid subjects whereas there is no significant difference in mean total bilirubin and mean total serum albumin between euthyroid and hyperthyroid subjects.
Conclusion: Thyrotoxicosis has a significant effect on liver that is reflected in increased level of liver specific enzymes i.e. AST and ALT.