A study to assess the hrql and biochemical changes among patients with alcoholic liver cirrhosis

Introduction: cirrhosis of liver disease is degenerative disease of liver the most common causes were alcohol, this study was done among patient with alcohol liver cirrhosis analysed their HRQL and biochemical variable changes such as SGOT and SGPT.
Objective of the study: To assess the health related quality of life and biochemical changes among patients alcoholic liver cirrhosis
Methods: research design was adopted for this study wad descriptive research design, sample size of 50 admitted in medical ward of K. C. G general Hospital, Bangalore. The sampling technique was used Convenience sampling technique. The tool were used section - A demographic Performa of the patient, section –B HRQL measured by using the chronic liver disease questionnaire and Section -C biochemical variables observed by using check list. Data was analyzed by using Descriptive and inferential statistics.
Results: The sample 50 was assessed their HRQL and Biochemical variables, in HRQL majority of the patients were had moderate HRQL 28 (56%), and 22 (44%) were had low HRQL. regarding the biochemical variables the mean of SGOT level were 115.32 + 40.34 , SGPT level were 58.98 + 21.14, out of 50 patients SGOT level 2 normal and SGPT values 8 patients were normal it shows that the patient were in advanced stage of and severe vitamin B deficit.
Conclusion: The study concluded that majority of the patient had moderate HRQL and Non of the subject had high HRQL whereas in biochemical changes SGOT / SGPT ratio were 2:1 level were SGOT levels were twice higher than SGPT values. Few of patients in advanced stage disease and patient Vitamin B6 deficit biochemical (SGOT, SGPT) variables shows look like normal.