The term ‘cholesterosis of the gall-bladder designates an interesting and fairly common condition in which the mucous membrane is infiltrated with a mixture of cholesterol esters and neutral fat. It is more common in females and relatively rare in young individuals. Cholesterolosis not necessarily will show high levels of serum cholesterol levels or the presence of cholesterol stones. This shows that it is possible for a patient to have cholesterolosis even in absence of risk factors presenting as acute cholecystitis, which validate further need to understand this rare form of an uncommon disease.
We present a case of 24 year old girl presenting with complaint of intermittent right hypochondrium for one week. The patient had complaints that were in favour of gallstones and were underwent sonography for confirmation. In sonography, there were no stones present but the GB wall was thickened, which again arises suspicion for the cause whether it is a neoplastic change or non-neoplastic condition. The patient underwent lap cholecystectomy and intra-operatively the GB was found to be oedematous and red from inside on cut section which was sent for HPE . Her histopathological report revealed cholesterolosis with acalculous cholecystitis.
This indicates that a patient can develop cholesterolosis even in absence of risk factors presenting as acute cholecystitis, which should be further investigated to understand this rare form of an uncommon disease.
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