Socioeconomic Effect of crude oil exploration in industrial Area of Anakpa communities in Uruan Local Government Area of was investigated in Akwa Ibom State, Nigeria. The essence was to determine the effect caused by crude oil exploration and exploitation activities in the affected industrial communities of Anakpa in Uruan Local Government Area of Akwa Ibom State, Nigeria. The study was undertaken between March-2016 and March -2018. Qualitative method which entails the use of questionnaires was employed to ascertain the effect of crude oil exploration in the affected communities. In view of the population of the community mentioned four hundred questionnaires were distributed accordingly in the affected community. The results obtained showed that the crude oil exploration activities undertaken by the international organization has brought negative environmental consequences to the affected communities. The remarkable ecological damages recorded over the years in the study areas had been attributed to crude oil exploration in the area. The accidental crude oil spillages recorded in the area has caused severe impact on agricultural activities. The decline in soil fertility and plant growth and development had been attributed to the exploration activities. The gradual decline in surface water quality also was confirmed to be caused by the crude oil exploration activities in the study area. Though however the neighbouring communities was selected as control, but result recorded during the stakeholder meeting with the opinion leaders in the community confirmed that the crude oil pollution does not posed any adverse effect on human health and development at the control site.Aprtfrom the effect mentioned above there was no health effect associated with the exploration activities in the five areas affected by crude oil exploration at the study site.