Role of platelet parameters in patients with dengue infection

Author: 
Neha Singh., Sweta and Uma Sharma

Background: Dengue is one of the arthropod borne viral diseases transmitted by female mosquito Aedes aegypti. Dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality.
Aims & Objectives: To study platelet parameters like MPV,PDW & PLCR in dengue positive infection and to correlate their relationship with the severity of the disease.
Material & Methods: Study was done on 80 consequetive dengue positive cases during the outbreak of dengue infection from July 2017 to October 2017 in Department of Pathology at FMHS, SGT University, Gurugram. The platelet parameters like platelet count, MPV, PDW & PLCR were noted using SYSMEX XN 550 analyser and was compared with severity of disease(DF/DHF/DSS).
Results: Relationship between platelet parameters like platelet count, MPV,PDW and P-LCR along with thrombocytopenia was made with the severity of the disease.
Conclusion: Platelet count is thus a predictive parameter of DF/DHF/DSS. Decrease platelet count, MPV,PDW & PLCR may be used as a probable indicator for dengue. Decrease MPV (<9fl) and increase PDW (>13fl) showed considerable sensitivity for dengue fever.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2018.13259.2355
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