A review on fast-dissolving oral film

Fast-dissolving oral films (OTFs) have emerged as a cutting-edge oral solid dosage form due to their numerous advantages over traditional tablets and capsules. These films dissolve rapidly in the oral cavity, typically within seconds to a minute, enhancing the effectiveness of the active pharmaceutical ingredients (APIs). They require less saliva to dissolve compared to fast-dispersing tablets, ensuring consistent and efficient drug delivery. Additionally, OTFs can be administered without the need for chewing, reducing the risk of choking and making them more user-friendly. Moreover, these films can be taken without water, offering a convenient and discreet way to administer medication anytime, anywhere. Depending on the film's thickness and the choice of the polymer matrix, the release of the medicine can be tailored to be more gradual. When placed on the tongue or in the oral cavity, OTFs can swiftly hydrate, adhere, and dissolve, facilitating rapid local or systemic drug delivery. This quick onset of action can be advantageous for medications that require immediate therapeutic effects. Due to consumer demand for fast-dissolving products over conventional tablets or capsules, OTFs have gained a significant position as an alternative dosage form in the pharmaceutical market. Fast-dissolving oral films represent a modern and patient-friendly alternative to traditional oral solid dosage forms. Their rapid dissolution, ease of administration, and customizable drug release profiles make them a valuable option for improving patient compliance and therapeutic outcomes. As technology and formulation techniques continue to advance, OTFs will likely become even more prevalent in the pharmaceutical industry, offering innovative solutions for drug delivery challenges.