A retrospective study and screening models for varicose veins

A varix is an abnormally dilated blood vessel with a tortuous course. Varices usually occur in the venous system, but may also occur in arterial or lymphatic vessels. Varicose veins have no specific cause. Varicose veins are more common in women than in men and are linked with heredity. Other related factors are pregnancy, obesity, menopause, aging, prolonged standing, leg injury and abdominal straining. Venous reflux is a significant cause; research has also shown the importance of pelvic vein reflux (PVR) in the development of varicose veins. Varicose veins in the legs could be due to ovarian vein reflux. There is increasing evidence for the role of incompetent perforator veins in the formation of varicose veins and recurrent varicose veins. Furthermore, in this we discussed about possible in vitro and in vivo screnning models available for varicose veins.