A prospective observation study in predicting the need for ventilatory support in organophosphorus poisoning

Background: This study will help us to identify the factors, which help in predicting the need for ventilator support in a patient with consumption of organophosphorus compound. The study was conducted on 100 patients admitted in Osmania General Hospital, Hyderabad. 100 patients diagnosed to have consumed organophosphorus compound poison were studied in relationship to the need for ventilator support. In the total target study of 100 patients, 36 patients required ventilator support. Patients with moderate and severe poisoning required higher doses of atropine as compared to those with mild poisoning. Dose of atropine greater than 150 mg within 48 hours of admission was associated with higher need for ventilator support.