Abstract: Candida has emerged as an important cause of nosocomial blood stream infections (BSI) Candidemia is a life threatening infection causing high mortality in admitted patients. The most common risk factors are use of intravenous catheter, followed by prolonged antibiotic use, immunosuppresion, invasive procedures. The most common species isolated was Candida albicans, but recent literature suggests “non-albicans candida (NAC)” as a major cause of candidemia.
Aim and Objective: The aim was to study the profile of patients with candidemia.
Material and Methods: This study was carried out in the department of Microbiology, Dayanand Medical College and Hospital for a period of one year (jan-dec2017) in patients >18yrs admitted in the hospital. Blood culture was taken from the patients clinically suspected with sepsis. Demographic details, risk factors and outcome within 30 days of admission were recorded in a predesigned proforma. Patients with blood culture positive for growth of yeast were included in the study. Identification and antifungal susceptibility was done in VITEK 2 System.
Results: A total of 92 patients who had candidemia were studied and prevalence was found to be 1.6/1000 admitted patients in the hospital. Among all the isolates obtained,NAC 66.3% were predominant than Candida albicans (33.7%). Candida tropicalis was (47.8%) predominant among NAC. Corelation of risk factors with outcome was studied and profile of discharged patients along with hospital stay showed significant difference (p-value<0.002) .Maximum mortality was seen during first week of hospitalisation
Impact Factor
2022: 6.012
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