Introduction: The prevalence of auto immune disorders especially that of thyroid gland has been increasing nowadays. Antibodies directed against thyroid peroxidase are an important cause of autoimmune thyroid diseases. Objective: To determine the thyroid hormone status and prevalence of antithyroid peroxidase antibodies in patients referred for evaluation of thyroid function from January 2013 to December 2015. Design: Retrospective study. Setting: The results of the patients who attended the Nuclear Medicine department, Government Medical College, Kozhikode, Kerala from January 2013 to December 2015 were analyzed. Results: Among the 1197 individuals, 794 (66.3%) were euthyroid, 116 hyperthyroid (9.7%) and 287 (24.0%) hypothyroid. Anti thyroperoxidase antibody was elevated in 49.12% of patients, out of which 66.3% were euthyroid, 9.7%hyperthyroid and 24% hypothyroid. Prevalence of antithyro peroxidase antibodies in euthyroid, hypothyroid and hyperthyroid was42.4%, 69.7% and 44% respectively. Among the antibody positive individuals, subclinical hypothyroidism was the most common abnormality detected (53.78%).Conclusion: Nearly 49% of subjects under evaluation for various thyroid disorders in a tertiary care hospital population showed the presence of elevated antithyro peroxidase antibody. Autoimmune thyroiditis should be considered as a major health problem and antithyro peroxidase antibody could be a useful tool in its evaluation.
Impact Factor
2022: 6.012
This work is licensed under a