Purpose: Lantana camara (Verbenaceae) is one of the most popular medicinal plant in the traditional medicine. Different parts of Lanata camara have been used for the treatment of various human ailments such as itches, cuts, ulcers, swellings, bilious fever, eczema, tetanus, malaria, tumor, rheumatism and headache. To evaluate the scientific basis for the use of the plant, the antimicrobial activity of leaves extracts were evaluated against some Gram negative and Gram positive bacteria.
Pharmacognostic characterization: Fresh leaf of Lantana camara was studied for microscopical characterization. Pulverized dried Lantana camara leaves were investigated for its physical constant (LOD, ash value, extractive values, fluorescence analysis) and extracted with ethanol using soxhlet apparatus and macerated with chloroform water.
Method: Antimicrobial activity of Lanata camara leaf extracts were studied by determination of the diameter of zone of inhibition against both Gram negative and Gram positive bacteria using agar disc diffusion and minimum inhibitory concentration (MIC).
Result: Phytochemical studies revealed the presence of alkaloids, glycosides, steroids, flavonoids, tannins and the extracts were active against both Gram positive and Gram negative bacteria. Ethanolic extract at dose 500mg/ml showed potent activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi when compared with aqueous extracts.
Impact Factor
2022: 6.012
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