Background: Oral contraceptive (OC) is one of contraceptives that widely used by family planning participant. OC consists of estrogen and progesterone. OC is one of the risk factors for glaucoma. The mechanism between sex hormone and glaucoma unclear, but many studies reported sex hormone receptors found in retinal ganglion cells.
Material and Methods: Prospective, analytical observational with cross sectional study was conducted at University as Sumatera Utara Hospital from April to September 2018 after approved by the Ethics Committee for Health Research. 77 samples (154 eyes) with history OC ≥ 3 years were included in this study. Intraocular pressure (IOP), retinal nerve fiber layer (RNFL) thickness and iridocorneal angle was measured by using Non contact Tonometry, Optical Coherence Tomography and Gonioscopy for diagnosed primary open angle glaucoma (POAG).
Results: There was a significantly differences between duration of OC use, IOP, and RNFL thickness with POAG (p = 0.0001), and there was no significantly differences between age OC users and POAG (p = 0.062).
Conclusion: OC is a risk factor for incidence of POAG. So, Obstetrics and Gynecologyst are advised to consult OC users to Ophthalmologist for evaluation.
Impact Factor
2022: 6.012
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