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Saprophytic Non-fermenting Gram negative bacilli have emerged as important healthcare associated pathogens.These organisms are ubiquitous in nature particularly in soil & water even found in hospital environment.This case series contains several cases of non-fermenters that were reported from Burdwan Medical College & Hospital within 15 days. The increasing multidrug resistance shown by these important pathogens leave us with fewer option to treat severe life threatening infections.