Impact of body mass index on liver enzymes in postmenopausal women

Objectives: To assess the correlation of BMI with liver enzymes in postmenopausal women.
Methodology: The study was conducted on 100 postmenopausal women in the age group of 45-55 years. Subjects were divided into 3 subgroups: Normal, Overweight and Obese on the basis of BMI. Body weight and height was taken and BMI was calculated using Quetlet index. Early morning Blood samples were taken after a minimum of 8 hours of fasting for assessment of liver enzymes AST and ALT. All parameters were reported as mean and standard deviation. The statistical differences in mean values were tested using Levene’ test for equality of variances followed by t-test for equality of means. ANOVA was used to do comparison with in the subgroups. Pearson correlation was used to calculate the correlation between various variables. A p-value <0.05 was considered statistically significant and p-value >0.05 was considered non-significant.
Conclusion: A highly significant correlation was seen between liver enzyme AST and BMI in normal, overweight and obese postmenopausal females. There is significant rise of AST levels in obese postmenopausal women.