Hemisection refers to sectioning of a mandibular molar into two halves followed by removal of the diseased root and its coronal portion. Hemisection of a mandibular molar may be a suitable treatment option when the persistent pain with calcification is restricted to one root and the other root is healthy. The retained root is endodontically treated and the furcation area is made self-cleansable. Retained tooth structure is restored as premolar which helps to reduce the masticatory load. The present case report explains the hemisection as one of the treatment modality in these type of cases and importance of PRF for preservation and enhancing the healing of extraction socket.