Functional outcome of bone substitutes for filling defects after extended curettage in benign lytic bone lesions- a retrospective analysis of 34 patients

Author: 
Umesh Yadav, Ajay Singh, Sujit Kumar Singh, Kshitish Chandra Behera, Ashish Devgan, Vasudha Dhupper and Ajay Sheoran

Background-Extended curettage remains the treatment of choice for most of benign bony lesions. Defect after curettage can be filled with autograft , allograft or bone substitutes. We hereby retrospectively analyzed functional outcome of bony lytic lesion in which bone substitutes were used.
Material and methods- 34 patients of benign bony lytic lesions limited to extremities were treated by extended curettage and finally defect was filled with β-Tricalcium phosphate (β-TCP). Patients were evaluated clinic-radiologically at regular intervals. Graft uptake was assessed using Irwin method while final functional outcome was assessed using Musculoskeletal Tumor Society Rating Scale (MSTS) Score.
Results- Mean age was 26±6.5 years ranging from 5-62 years. . Aneurysmal bone cyst was found to be the most common diagnosis (n=14, 41.2%) followed by Giant cell tumor (n=10, 29.4%). Femur was most commonly affected bone (n=8, 23.5%) followed by radius (n=6, 17.6%). 76.5% patients achieved Irwin Grade III. Mean healing time was 10.2±2.2 weeks. The overall average Musculoskeletal Tumor Society (MSTS) score was 26.8 (range 23–30).
Conclusion- Bone substitutes remains a good choice in filling defect after curettage for benign lytic bony lesions specially in children and elderly patients in whom harvesting of autograft is not feasible.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2020.22488.4437
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