Introduction: In an era of liver transplantation, being readily available at major metro cities in India, the need for optimal prioritization of organ transplant waiting list has become more than a far-fetched reality. This article is a part of study done on patients presenting with end of line spectra of liver diseases, both acute and chronic(acute liver failure, acute on chronic liver failure and decompensated cirrhosis) to evaluate their descriptive markers which govern the morbidity and mortality and hence helpful in prioritizing the waiting list. Objectives of this study is to study the the descriptive clinico-laboratory markers of prognosis and their relationship with acute mortality(within 30 days of admission) and morbidity(number of days of hospital stay in a month) in patients of decompensated cirrhosis and to determine and compare the diagnostic performance of these clinico-laboratory markers to ascertain acute mortality (within 30 days of admission ) and morbidity. Methodology: The study was a prospective descriptive and observational study, which included the indoor patients admitted under department of medicine, Gandhi medical college Bhopal, who fulfilled selection criteria(inclusion and exclusion) .A written informed consent was taken and their clinical and laboratory parameters at the time of admission and during the course of hospital stay were recorded. These patients were followed up till a period of 1 month from admission to note outcomes.Results and conclusion: In patients of decompensated cirrhosis markers of acute inflammation (neutrophil to lymphocyte ratio, C-reactive protein , Q-SOFA) had better diagnostic performance than MELD score and serum sodium levels for predicting short term mortality. When these markers were assesed to predict morbidity in terms of total number of days spent in hospital in a month, significant correlation was found only with higher MELD score and low seum sodium levels.
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2022: 6.012
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